NL-OMON32126
Completed
Not Applicable
Incidence of colorectal lesions in first degree relatives of patients with hyperplastic polyposis syndrome (HPS) - PROTECT
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 55
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •First\-degree relatives (\* 35 years of age or 5 years younger than the lowest incidence age) of patients under surveillance at the Endoscopy Department of the AMC with HPS, defined as:
- •1\) \*10 HPs found at colonoscopy, or
- •2\) \*5 HPs proximal to the sigmoid colon of which 2 are greater than 10mm in diameter, or
- •3\) Any number of HPs occurring proximal to sigmoid colon in an individual who has a first\-degree relative with hyperplastic polyposis
Exclusion Criteria
- •Exclusion criteria are 1\) individuals who have undergone a colonoscopy in the past three years 2\) individuals who have undergone a colectomy 3\) severe co\-morbidity and 4\) age less than 35 years.
Outcomes
Primary Outcomes
Not specified
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