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临床试验/CTRI/2026/01/100729
CTRI/2026/01/100729尚未招募2 期

COMPARATIVE EFFICACY OF A POLYHERBAL UNANI FORMULATION AND SHARBAT E TOOT SIYAH IN THE MAMAGEMENT OF WARAM AL LAWZATAYN MUZMIN CHRONIC TONSILLITIS A RANDOMIZED CLINICAL STUDY

State unani medicine college and hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年1月10日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Reduction in clinical scoring system.

研究概览

简要总结

The term Lawzah originates from Arabic and refers to Gudud gland In modern medicine, the word tonsil derives from Latin, meaning swelling

Tonsils are clusters of lymphoid tissue located in the throat that play a key role in local immunity and serve as a first line of immune surveillance helping to prepare the entire body for defense The tonsils commonly referred to as the palatine or faucial tonsils which are situated in the tonsillar fossa between the palatoglossal and palatopharyngeal arches

Waram e Lawzatayn tonsillitis refers to the inflammation of the tonsils which may also extend to involve the adenoid and lingual tonsil

Chronic tonsillitis is defined as a condition in which a person experiences seven or more episodes of acute tonsillitis in a year

Tonsillitis is more commonly observed in school aged children though it can frequently occur in adults as well Key predisposing factors include poor nutrition and inadequate oral and dental hygiene The condition is most often caused by persistent or recurrent infections of the nose and paranasal sinuses which result in postnasal discharge that subsequently infects the tonsils Common symptoms include throat discomfort bad breath halitosis and an unpleasant taste in the mouth On physical examination the tonsils may appear enlarged and protrude beyond the tonsillar pillars Tonsillitis is rarely seen in infants and individuals over the age of 50

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 39.00 Year(s)(—)
性别
All

入选标准

  • Patients of either gender in the age group of 18 to 39 years.
  • Clinically diagnosed cases of Waram al-Lawzatayn Muzmin chronic tonsillitis.
  • Disease severity with Clinical Scoring System Severe equal or more than 9 Moderate 4 to 8 Mild equal or more than 3 Patients who will give consent and able to do follow up.

排除标准

  • Pregnant and lactating women.
  • Patient with any complication of tonsillitis.
  • Tonsillitis associated with any other systemic metabolic or chronic disease.
  • Patients unsure about attending schedule regularly.
  • Patients who have received any antibiotic therapy within the last 2 weeks will be excluded from the study.

结局指标

主要结局

Reduction in clinical scoring system.

时间窗: At Baseline | 2nd week | 4th week | 6th week

Improvement in patient global assessment on visual analog scale (VAS).

时间窗: At Baseline | 2nd week | 4th week | 6th week

次要结局

  • Tonsillectomy Outcome Inventory 14

研究者

发起方
State unani medicine college and hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Saara Naaz

State Unani medical College and hospital

研究点 (1)

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