Impact of a Berry Extract on Vascular Functio

Not Applicable

Recruiting

• Conditions: Overweight; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12616000270415
• Lead Sponsor: Dr Kade Davison

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-03-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Men aged over 45 years of age and post­menopausal women.
2. BMI between 26.9 and 29.99
3. Blood pressure less than 140/90 mmHg
4. Able and willing to give informed consent and comply with all study protocol procedures.

Exclusion Criteria

1. More than 150 min/week of moderate activity or more than 75 min/week of intense activity
2. Taking vasoactive medications (e.g. statins, aspirin, blood pressure lowering drugs) or food supplements (e.g. fish oil)
3. Smoking
4. Weight loss of more than 10% body weight in the previous 6 months
5. Currently treated with a diet for weight loss
6. Reported participation in another study within 1 month before the study start
7. Chronic­-acute disease, including any kind of metabolic abnormality or major cardiovascular risk factor or both.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Flow­-mediated dilation, measured using a two dimensional B-mode ultrasound[The beginning and end of each 14­ day supplementation period (both fasted and 1hr following consumption of supplement).]

Secondary Outcome Measures

Name	Time	Method
Blood pressure, measured using an oscillometric device[The beginning and end of each 14­ day supplementation period];Arterial stiffness, measured using a Sphygmocor device[The beginning and end of each 14­ day supplementation period];Cerebrovascular reactivity measured using transcranial doppler ultrasonography[The beginning and end of each 14­ day supplementation period]