Surgical Evacuation of First Trimester Missed Miscarriage With or Without Use of Transabdominal Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Measurement of endometrial thickness by ultrasound (mm)
研究概览
简要总结
Abortion is considered the most common cause of fetal demise all over the world. The majority of cases occur in the first trimester. The termination of abortion may be by medical or surgical methods, however; the surgical methods represent the greater part of termination. Therefore, the safety of this procedure is a worldwide public health concern. Many clinical studies have reported the safety of surgical evacuation in the first trimester.
The suction-aspiration or vacuum aspiration is the most common surgical method of induced abortion. This consists of removing the fetus, embryo, placenta, and membranes by suction using a manual syringe or electric pump. However; these techniques always need cervical dilation before aspiration. The menstrual extraction does not require cervical dilation and can be used in very early pregnancy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women with non-viable first trimester intrauterine pregnancy
- •no contraindication to surgical evacuation under general anesthesia
排除标准
- •gestational age more than 13 weeks
- •hemodynamically unstable
- •suspicion of an ectopic pregnancy
研究组 & 干预措施
Blinded evacuation
Ring evacuation was performed in the conventional way without use of ultrasound followed by sharp gentle curettage until complete evacuation
干预措施: Blinded evacuation (Procedure)
Evacuation under ultrasound guidance
Ring evacuation was performed under ultrasound guidance followed by sharp gentle curettage until complete evacuation. The surgery was considered complete when the endometrial cavity appeared as a regular echogenic line.
干预措施: Evacuation under ultrasound guidance (Procedure)
结局指标
主要结局
Measurement of endometrial thickness by ultrasound (mm)
时间窗: 1 month
次要结局
- Measurement of blood loss (mL)(1 month)
- measurement of operative time (minutes)(1 month)
- measurement of Hemoglobin level(g/ml)(1 month)