TRUMPRWS: A Non-interventional Study on Genetic Variants and Its Clinical Relevance in Chinese Patients With Advanced NSCLC (TRUMPRWS)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 2,700
- 试验地点
- 1
- 主要终点
- Clinical relevance between genomic profiling and overall survival
研究概览
简要总结
This is a descriptive observational study, in which data are collected in an epidemiological fashion. This study does not intend to alter or intervene the current medical practice of the recruited patients. Data will be collected in prospective manner.
详细描述
This is a descriptive observational study, in which data are collected in an epidemiological fashion. This study does not intend to alter or intervene the current medical practice of the recruited patients. Data will be collected in prospective manner.
The eligible patients will be recruited after NGS analysis for tumor tissue and the inform-consent is obtained. The study required information will be collected (every 3 months).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must be ≥20 years of age.
- •Provision of fully informed consent prior to any study specific procedures.
- •Histologically or cytologically confirmed, unresectable stage IIIB or stage IV NSCLC.
- •Genetic variants of tumor tissue detected by NGS.
排除标准
- 未提供
结局指标
主要结局
Clinical relevance between genomic profiling and overall survival
时间窗: [ Time Frame: From registration onto that step until death, or censored at the date of last contact, assessed up to 3 years]
Kaplan-meier analysis of overall survival based on different genetic alteration
次要结局
- The characteristics of genomic variation and dynamic changes during different anti-tumor treatment(24 months)