Comparison of the effect of PRP and Prolotherapy on symptom control in patients with temporomandibular joint disorders

Not Applicable

• Conditions: Temporomandibular joint disorders.; Temporomandibular joint disorders; M26.6

• Registration Number: IRCT20210306050604N2
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

A history of chronic temporomandibular joint pain and a clicking sound in one or both sides and decreased mouth opening that started at least 3 months ago and has not responded to conservative treatment
No evidence of intra-articular pathological problems on open and closed-mouth dynamic MRI
Do not be allergic to corn
Do not have inflammatory connective tissue disease, neurological disorders, severe anemia, thrombocytopenia or malignant diseases of the head and neck
Do not have masticatory muscle problems and muscle tenderness and a previous history of open joint surgery
Do not have problems with dental origin in OPG

Exclusion Criteria

Patients who do not agree with the injection protocol

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient pain in temporomandibular joint. Timepoint: Days 0 (before the start of the study), 14, 30, 60, 90. Method of measurement: Visual Analogue Scale ( VAS ).;Maximum mouth opening rate. Timepoint: Days 0 (before the start of the study), 14, 30, 60, 90. Method of measurement: millimetre.;Joint clicking sound. Timepoint: Days 0 (before the start of the study), 14, 30, 60, 90. Method of measurement: 0: No sound-1: Subjective sound / can be heard with a stethoscope-2: A sound that can be heard without a stethoscope.