Long Term Results in Redo Mitral Valve Surgery After Mitral Valve Repair
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Degenerative Mitral Valve Disease
- Sponsor
- Michele De Bonis
- Enrollment
- 108
- Locations
- 1
- Primary Endpoint
- Survival after reintervention
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The current gold standard for severe mitral regurgitation is mitral valve plasty (PLM). The surgery allows the repair of the mitral valve, therefore without the need for mitral valve replacement (SVM), which involves the implantation of a biological prosthesis or a mechanical prosthesis.
However, PLM has a rate of failure, between 1-4% per year in degenerative mitral pathologies. As a result, patients with PLM failure and severe residual regurgitation are increasingly presenting in recent years.
Generally these patients are re-operated to replace the mitral valve. Our aim is to investigate the differences in re-operation involving mitral valve replacement or re-repair in patients who underwent mitral valve re-operation (re-repair or replacement) in our center between 2003 and 2017.
Investigators
Michele De Bonis
Chief of Cardiac Surgery of Advanced and Research Therapies
Ospedale San Raffaele
Eligibility Criteria
Inclusion Criteria
- •adult patients
- •failure of previous mitral valve repair which needed a new surgical treatment
- •group Re-PLM: patients reoperated with a new mitral valve repair
- •group Re-SVM: patients reoperated with a mitral valve replacement
Exclusion Criteria
- •urgent/emergent procedures
Outcomes
Primary Outcomes
Survival after reintervention
Time Frame: through study completion, a minimum of 2 years
Time of survival after reintervention for failed mitral valve repair
Secondary Outcomes
- Risk factors for reintervention(through study completion, a minimum of 2 years)