Long Term Results in Redo Mitral Valve Surgery After Mitral Valve Repair
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- Survival after reintervention
研究概览
简要总结
The current gold standard for severe mitral regurgitation is mitral valve plasty (PLM). The surgery allows the repair of the mitral valve, therefore without the need for mitral valve replacement (SVM), which involves the implantation of a biological prosthesis or a mechanical prosthesis.
However, PLM has a rate of failure, between 1-4% per year in degenerative mitral pathologies. As a result, patients with PLM failure and severe residual regurgitation are increasingly presenting in recent years.
Generally these patients are re-operated to replace the mitral valve. Our aim is to investigate the differences in re-operation involving mitral valve replacement or re-repair in patients who underwent mitral valve re-operation (re-repair or replacement) in our center between 2003 and 2017.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients
- •failure of previous mitral valve repair which needed a new surgical treatment
- •group Re-PLM: patients reoperated with a new mitral valve repair
- •group Re-SVM: patients reoperated with a mitral valve replacement
排除标准
- •urgent/emergent procedures
结局指标
主要结局
Survival after reintervention
时间窗: through study completion, a minimum of 2 years
Time of survival after reintervention for failed mitral valve repair
次要结局
- Risk factors for reintervention(through study completion, a minimum of 2 years)
研究者
Michele De Bonis
Chief of Cardiac Surgery of Advanced and Research Therapies
Ospedale San Raffaele