Effects of the breathing response during reduced oxygentension in inspired air and simultaneous infusion of a neuromuskular blocking agent in patients with obstructive sleep apnea - before and after three months of continous positive airway pressure treatment.
- Conditions
- Obstuctive sleep apnea and acute hypoxic ventilatory responseMedDRA version: 14.1Level: LLTClassification code 10055577Term: Obstructive sleep apnea syndromeSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disordersTherapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2011-005792-16-SE
- Lead Sponsor
- Karolinska University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- Male
- Target Recruitment
- Not specified
Inclusion Criteria
Men with diagnosed and untreated moderat obstruktive sleep apnea syndrom (corresponding to AHI (apnea-hypopnea index) 15-30). The men must otherwise be healthy. 18-60 years of age. Non-smokers. BMI <33. They have to sign informed consent.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 20
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Those who do not fulfill the inclusion criterias. Allergy for neuromuscular blocking agents.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method