Effect of whitening cream on melasma
Phase 3
- Conditions
- Melasma.Chloasma
- Registration Number
- IRCT2016121031288N2
- Lead Sponsor
- Jarfandishan-e Navid-e Salamat (Janus) knowledge-based company
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Inclusion : Case of moderate to severe melasma (MGSC>2); age range 18-50 (men or women); signed informed consent voluntarily and knowingly Exclusion :pregnancy or lactation? use of systemic corticosteroid, isotretinoin within 28 days prior to the study; use any light sensitive drug within 3 months prior to the study? Active skin disease at test area: rosacea, atrophy, acne, eczema; Use of topical lightening products like AHA ,BHA and retinoid component within 21 days prior to the study; Documented allergies to components of Januluma cream? Use of contraceptive or any hormonal drugs? History of laser treatment or dermabrasion or deep facial peels within the past 3 months
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Modified melasma severity index. Timepoint: Before intervention, one month later, two month after intervention. Method of measurement: mMASI.
- Secondary Outcome Measures
Name Time Method Skin pH. Timepoint: before and after 4and 8 weeks. Method of measurement: MPA 580.;Skin sebum. Timepoint: Before and after 4and 8 weeks. Method of measurement: MPA 580.;Skin melanin and erythem. Timepoint: before and after 4 and 8 weeks. Method of measurement: MPA 580.;TEWL. Timepoint: before and after 4 and 8 weeks. Method of measurement: MPA 580.;Size and value of skin spot. Timepoint: before and after 4 and 8 weeks. Method of measurement: Visioface.