Using Anogenital Distance to Determinate Fetal Gender Beetween 18 et 41 Weeks of Gestation.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 318
- 试验地点
- 1
- 主要终点
- fetal anogenital distance
研究概览
简要总结
The purpose of this study is to determine a threshold value of fetal anogenital distance in 2D ultrasound to differentiate male fetuses from female fetuses, starting 18 weeks of gestation and until the due date.
The study also evaluates the feasibility of the measure and its interobserver variability.
详细描述
The anogenital distance of female newborns is shorter than that of male newborns.
Urogenital disorders, such as hypospadias and micro-penis, are associated with a shorter anogenital distance.
Anogenital distance is a good marker of fetal exposure to androgenic substances.
Prenatal anogenital distance ultrasound measure can help the diagnosis in case of doubt about fetal sexual phenotype or in case of urogenital disorder suspicion (hypospadias or micropenis).
Is the anogenital distance easy to make measure? Can this procedure be reproduced? What are the threshold values to determine fetal sex at each term of pregnancy?
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •pregnant woman
- •sonographic fetal follow up in Brest Hospital
- •term>18 weeks of gestation
排除标准
- •No datation between 11 weeks of gestation and 13 weeks of gestation and 6 days by crown-rump length measurement
- •no consent
- •ultrasound performed by an operator without ultrasonography graduation
结局指标
主要结局
fetal anogenital distance
时间窗: During fetal ultrasound exam
The distance will be measured from the center of the anus to the posterior convergence of the fourchette in female fetuses and to the posterior base of the scrotum in male fetuses
次要结局
- Estimated fetal weight(During fetal ultrasound exam)
- Ano-genital distance in mm(During fetal ultrasound exam)
- Interobserver variability(During fetal ultrasound exam)
- neonatal sex determination(During fetal ultrasound exam)