A study to determine the eight-week longitudinal variation in serum periostin levels in a population with stable asthma.

Not Applicable

Completed

• Conditions: Periostin levels, in stable asthmatics; Respiratory - Asthma

• Registration Number: ACTRN12614000235606
• Lead Sponsor: Medical Research Institute of New Zealand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-03-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Aged between 18 to 75 years
Able to provide written informed consent
Doctor diagnosis of asthma
On a stable asthma treatment regime for greater than or equal to 3 months prior to visit 1, taking regular inhaled medication for asthma (including maintenance inhaled corticosteroid and long acting beta agonists)

Exclusion Criteria

Unstable asthma (as determined by the investigator and/or a change in asthma medication in last 3 months)
Oral or Systemic Corticosteroids within the last 3 months
Known Pregnancy
Significant co morbidities (determined at investigator discretion)
Hospital admission within last 3 months
Surgery within last 3 months, determined at investigator discretion (this includes all major surgery requiring general anaesthetic, dental extractions and root canal procedures. This does not include minor procedures, including but not limited to mole or wart removal, dental fillings etc).
Bone fracture within the last 3 months
Active (current, or within the 3 weeks prior to the visit) upper or lower respiratory tract infection
Any other safety concern at the investigator’s discretion

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ongitudinal variation in serum periostin level over an eight-week period.[Serum perisotin will be measured at Days: 1 [enrolment visit], 2, 3, 4, 5, 10, 17, 24, 31, 38, 59 ]