COMPARING EFFICACY OF TWO DIFFERENT DOSES OF FENTANYL FOR PREVENTING HYPERTENSION AND TACHYCARDIA WHILE GIVING GENERAL AENESTHESIA
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/03/031837
- Lead Sponsor
- Government of Gujarat
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Informed written consent.
Patients posted for elective surgery under general Anesthesia requiring endotracheal intubation.
ASA physical status ||
Well controlled primary idiopathic hypertension(blood pressure less then or equal to 140/90) with maximum three anti hypertensive medications excluding beta blockers.
No end organ involvement due to hypertension.
BMI less then or equal to 25.
Modified Mallampati classification | and ||.
Patient refusing for consent.
Patients with diabetes, COPD, renal disease, cardiac diseases like IHD, valvular heart disease, AV conduction block, aortic stenosis, left ventricular failure etc.
Patient on drugs(sedatives,opioids,anti-psychotic drugs and beta blockers).
Anticipated difficult intubation.
BMI more then or equal to 25.
Intubation attempt lasting longer than 15 seconds.
Patient on more than 3 anti hypertensive medications.
Defaulter of taking anti hypertensive medications as per schedule.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Variation in heart rate, systolic blood pressure, diastolic blood pressure, ST-T changes, cardiac rhythm changesTimepoint: From injection of intravenous fentanyl to 20 minutes after endotracheal intubation
- Secondary Outcome Measures
Name Time Method To asses sedative effect of fentanyl and to observe any complicationsTimepoint: From injection of intravenous fentanyl to 60 minutes after endotracheal extubation