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The effect of dialectical behavior therapy in autism spectrum patients with suicidality and/or self destructive behaviour: a multi-site randomized controlled trial.

Completed
Conditions
autism
suicidality and destructive behavior
10012562
Registration Number
NL-OMON53092
Lead Sponsor
Vrije Universiteit
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
128
Inclusion Criteria

1) age between 18 and 65 years
2) Meets DSM V criteria for autism spectrum disorder
3) Suicidal and / or self destructive behavior have shown in year before
starting treatment
4) Sufficient mastery of the Dutch language
5) Outpatient

Exclusion Criteria

1) IQ <80
2) Addiction to illicit drugs in need of clinical detoxification

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The first objective is to asses the effect of a short term DBT treatment<br /><br>program (26 weeks) versus treatment as usual, in terms of reduction of suicidal<br /><br>and/or self-harming behaviour in adult patients with autism</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondly, the effects of DBT treatment are determined on anxiety and social<br /><br>performance, depression, core symptoms of ASD,<br /><br>quality of life and cost-effectiveness and cost-utility.<br /><br><br /><br>Thirdly, predictors, moderators, and mediators for treatment success will be<br /><br>explored. These include emotion regulation; strength of the therapeutic<br /><br>alliance; difficulties engaging in goal-directed behaviours; demographic<br /><br>characteristics and alexithymia</p><br>
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