NCT03577327
Recruiting
Not Applicable
The Gut and Skin Microbiome in Vitiligo Disease Progression
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Vitiligo
- Sponsor
- Northwestern University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Microbiome composition
- Status
- Recruiting
- Last Updated
- 12 months ago
Overview
Brief Summary
Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls. The investigators aim to answer the question whether the gut and skin microbiome of patients with vitiligo differs from the general population.
Investigators
I Caroline Le Poole
Professor
Northwestern University
Eligibility Criteria
Inclusion Criteria
- •Patients with and/or without vitiligo lesional expansion over the past year.
- •Age/sex-matched controls who do not have a diagnosis of vitiligo
- •Subjects who are age 18-89 years of age at time of enrollment
- •Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443)
Exclusion Criteria
- •Subjects who are younger than 18 years of age or 90 years of age or older
- •Subjects who are unable to give consent
Outcomes
Primary Outcomes
Microbiome composition
Time Frame: 12 months
Diversity analysis of microbiome samples in control subjects versus vitiligo subjects (measured by number of bacteria species/sample)
Disease Progression
Time Frame: 12 months
Disease progression in control subjects versus vitiligo subjects (measured by VASI score (0-100)).
Secondary Outcomes
- Diet History Food Frequencies(12 months)
Study Sites (1)
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