Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD)

Not Applicable

• Conditions: GVHD, Chronic; GVHD,Acute
• Interventions: Other: Physical exercise

• Registration Number: NCT05401955
• Lead Sponsor: University of Salamanca

Brief Summary

Range of motion, antropometric measurements, quality of life questionnaire and 2 minutes walk test will be implemented as an initial assessment.

Physical exercise program will take 2 sessions a week for six months, and several follow-ups: before, during and after treatment.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-05
• Study Start: 2022-05-01
• Primary Completion: 2022-05-10
• Study First Submitted: 2022-05-12
• Study First Submitted QC: 2022-05-27
• Last Update Submitted: 2022-05-27
• Study First Posted: 2022-06-02
• Last Update Posted: 2022-06-02
• Study Completion: 2023-07-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Allogenic Transplantation patients with Graft versus host disease

Exclusion Criteria

• Cognitive impairment
• Physical limitation from other pathologies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Graft versus host disease Group	Physical exercise	-

Primary Outcome Measures

Name	Time	Method
SF36 Questionnaire	baseline and post-intervention (24 weeks)	Quality of life
Hands strength	baseline and post-intervention (24 weeks)	Dynamometer
2 minutes walk test	baseline and post-intervention (24 weeks)	walking for 2 minutes without rest
Active range of motion	baseline and post-intervention (24 weeks)	P-ROM. Active ROM will be compared with standard pictures (1-4 points for lower limb and 1-7 points for upper limb)

Trial Locations

Locations (1)

University of Salamanca; 🇪🇸 Salamanca, Spain