Family Motivational Intervention in Schizophrenia

Not Applicable

• Conditions: Cannabis; Schizophrenia
• Interventions: Behavioral: Family Motivational Intervention

• Registration Number: NCT01167556
• Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Brief Summary

Cannabis use by people with schizophrenia is associated with family distress and poor clinical outcomes. Therefore, an Family Motivational Intervention (FMI) was developed to help parents to motivate their child with a diagnoses of recent-onset schizophrenia to reduce cannabis use.

In a single-blind randomised clinical trail with 75 patients with the diagnosis of schizophrenia, parents will be assigned to either FMI or to routine care. Assessments will be conducted at baseline and at a 10- and 22-month follow-up. The study hypothesis is that FMI will be more effective than routine care in reducing (a) cannabis use in patients and (b) distress and sense of burden in parents.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-03
• Status Verified: 2008-02
• Study First Submitted: 2010-07-20
• Study First Submitted QC: 2010-07-21
• Last Update Submitted: 2010-07-21
• Study First Posted: 2010-07-22
• Last Update Posted: 2010-07-22
• Primary Completion: 2010-08
• Study Completion: 2011-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 147

Inclusion Criteria

• Clinical diagnosis of schizophrenia or psychotic-related disorder
• Onset of schizophrenia or related disorder within pervious the 10 years
• Cannabis use at least 2 days per week in the 3 months prior to the assessment
• Antipsychotic medication in prescribed or indicated
• At least 10 hours of contact with the parents each week in the last month

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Family Motivational Intervention	Family Motivational Intervention	An intervention provided to parents consisting of 6 sessions of training in Interactions Skills and 6 sessions training in Motivational Interviewing.
Routine care for parents	Family Motivational Intervention	Routine care for parents consisting of 2 sessions psycho-education and individual support

Primary Outcome Measures

Name	Time	Method
Cannabis use in patients with a diagnosis of recent-onset schizophrenia	22-month follow-up (15 months after the intervention has ended)

Secondary Outcome Measures

Name	Time	Method
Medication adherence in patients with a diagnosis of recent-onset schizophrenia	22-month follow-up (15 months after the intervention has ended)
Quality of life in patients with recent-onset schizophrenia	22-month follow-up (15 months after the intervention has ended)
Stress in parents due to caring for a child with recent-onset schizophrenia	22-month follow-up (15 months after the intervention has ended)
Expressed emotion in parents of patients with recent-onset schizophrenia	22-month follow-up (15 months after the intervention has ended)

Trial Locations

Locations (1)

Academic Medical Center; 🇳🇱 Amsterdam, North Holland, Netherlands