DRKS00014989
Completed
未知
Effect of different anesthetic regimens on the renoprotective effects of remote ischemic preconditioning (RIPC) in high- risk patients undergoing cardiac surgery - HypnoRenalRIP
niversitätsklinikum MünsterKlinik für Anästhesiologie, operative Intensivmedizin und Schmerztherapie0 sites160 target enrollmentOctober 9, 2019
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- OPS-2013:5-35 (Operations on valves and septa of the heart and vessels near the heart, 5-361 (creation of an aortocoronary bypass)
- Sponsor
- niversitätsklinikum MünsterKlinik für Anästhesiologie, operative Intensivmedizin und Schmerztherapie
- Enrollment
- 160
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients with coronary heart disease and/ or heart valve disease and an increased risk for the development of a postoperative AKI (Cleveland score \= 6\) who have to undergo cardiac surgery with the use of the heart\- lung machine.
- •2\. Written informed consent of patient.
Exclusion Criteria
- •Acute myocardial infarction \= 7 days before surgery
- •Off pump heart surgery
- •Pre\- existing AKI
- •chronic kidney disease with eGFR \< 30 ml/min
- •Prior kidney transplant within the last 12 months
- •Peripheral vascular disease affecting the upper limbs
- •Hepatorenal syndrome
- •Drug therapy with sulphonamide (incl. Thiazides) within the last 7 days
- •Participation in another intervention study in the last 30 days
- •Persons with any kind of dependency on the investigator or employed by the sponsor or investigator
Outcomes
Primary Outcomes
Not specified
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