Vitamin-D level in sepsis and its outcome in patients admitted in medical intensive care unit - NI

Research and development department, Datta Meghe institute of higher education and research0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月1日

研究概览

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•After written inform consent all the patients of more than 18 years of age who will be screened clinically for sepsis and low vitamin D levels, relevant biochemical analysis will be done and they will be considered for study if they met the accepted definition for sepsis:
•1) confirmed or suspected source of infection determined by the treating clinician and/or a serum lactate level .2.5 mmol/L1.
•2) Two or more criteria for the systemic inflammatory response syndrome (SIRS), defined as:
•a) Temperature greater than 38C or less than 36C1.
•b) Respiratory rate greater than 20 breaths per minute or partial pressure of carbon dioxide less than 32 mm Hg1.
•c) Heart rate greater than 90 beats per minute1.
•d) White blood cell count greater than 12,000 or less than 4,000 cells per mm3, or greater than 10% immature forms1
•3) Presence of hypotension (mean arterial pressure,70 mm Hg or systolic blood pressure,90 mm Hg) despite adequate fluid resuscitation or requiring vasopressor therapy1.
•In the inclusion criteria, patients will be further divided into classes according to the values of Vitamin D:
•Reference level : 30ng/ml.
•Insufficient : 20-29ng/ml.
•Deficient :11-20ng/ml
•Severely deficient : less than 10ng/ml12.

发起方

Research and development department, Datta Meghe institute of higher education and research