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Clinical Trials/NCT00780364
NCT00780364TerminatedNot Applicable

Sour Taste and Cold Temperature Effects on Pharyngeal Transit Time After Ischemic Stroke:Anatomic and Functional Bases.

UPECLIN HC FM Botucatu Unesp1 site in 1 country30 target enrollmentStarted: March 2008Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Terminated
Sponsor
Enrollment
30
Locations
1
Primary Endpoint
Sour Taste and Cold Temperature in Dysphagia

Study Overview

Brief Summary

The objective is to establish the effect of sour taste and cold temperature on the pharyngeal swallowing transit time after ischemic hemisphere stroke.

Detailed Description

Over the past decade there were many studies over normal and pathological swallowing that discuss the influence of taste and temperature. Nevertheless there were many questions on the issue that remains to be solved, including the hemispheric lateralization of lesions dysphagic patients remains also to be fully understood.Swallowing disorder is defined as oropharyngeal dysphagia in presence of alterations in any phase of the complex swallowing dynamics. It could be congenital or acquired, affecting nutritional aspects, hydration, lung function and the individual's social integration [1]. Stroke, has a high incidence among neurological diseases, and cause disturbs on swallowing dynamics presenting signs of dysphagia in at least 50% of cases.A study that analyzed swallowing dynamics by videofluoroscopy in individuals with history of one or more stroke episodes with oropharyngeal dysphagia shows shorter pharyngeal and oropharyngeal transit times with cold stimulus than without them. Other study of heterogeneous neurological diseases such as cerebral palsy, brain trauma, stroke, and Alzheimer's disease, concluded that sour taste improved swallowing, minimizing laryngotracheal penetration and aspiration in individuals with neurological damaged. Chen et al. in an analysis of 42 healthy individuals with several taste bolus found that awareness and arousal could also influence the swallowing function.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
50 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Clinical diagnosis of stroke

Exclusion Criteria

  • •instability clinic

Outcomes

Primary Outcomes

Sour Taste and Cold Temperature in Dysphagia

Time Frame: 24 months

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
UPECLIN HC FM Botucatu Unesp
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Paula Cristina Cola

PhD

UPECLIN HC FM Botucatu Unesp

Study Sites (1)

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