Comparative evaluation of efficacy of the Malva sylvestris and Alcea digitata formulation with Hypozalix (artificial saliva) in the radiation induced xerostomia and quality of life in patients with head– and– neck cancers

School of Traditional Medicine, Traditional Medicine and Materia Medica Research Center,Shahid Behes0 个研究点目标入组 60 人开始时间: 待定最近更新: 2018年2月22日

试验速览

暂无简介。

•xerostomia at least grade 1 based on clinical grading CTC; adverse event 4; age between 20 to 70 years old; physically and mentally able to fill out a questionnaire; willingness to participate in the study and informed consent; at least three months after the end of radiotherapy; not drinking alcohol; drugs affecting the salivary glands like antidepressant, opioids, antihypertensive, antihistamines, diuretics, all kind of mouthwash and artificial saliva; no history of connective tissue disease like Sjogren, rheumatoid arthritis, lupus, liver disease, kidney disease, major depression, diseases involving salivary glands, diabetes, chronic diseases such as diarrhea cause dehydration; the absence ofneutropenia, immunosuppression, myelosuppression
•Exclusion criteria: sudden changes in systemic conditions like that a patient requires extensive chemotherapy and surgical interventions; failure/ need parenteral nutrition (TPN) or hospitalization; unwillingness to continue participation in the study.

发起方

School of Traditional Medicine, Traditional Medicine and Materia Medica Research Center,Shahid Behes