Effect of microneedling and topical basic fibroblast growth factor in treatment of stretch marks

Phase 3

Recruiting

• Conditions: Stria distensa.; Striae atrophicae; L90.6

• Registration Number: IRCT20220924056033N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patents between 18 and 60 years old

Exclusion Criteria

Pregnant women
Lactating women
Diabetic
Hypertension
Hypothyroidism
Hyperthyroidism
Immunosuppressed patients
Patients who recieved stria treatment 3 months ago or have infection on the stria

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical improvement stria. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: The GAIS(Global Aesthetic Improvement Scale) is measured as follows:Grade 0: worsening of lesions Grade1: No change (< 25% improvement)Grade 2: Improved (25-50% improvement)Grade 3: Much improved (51-75% improvement)Grade 4: Very much improved (76-100% improvement).

Secondary Outcome Measures

Name	Time	Method
Stria size reduction. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: Rate of width reduction (%)=Baseline width-Follow upwidth/Baseline width ×100.;Stria color. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: Melanin index is measured bySkinColorCatch colorimeter(Delphin, Finland) and is presentedas average of .3 points measure.;Patient satisfaction. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: Patient satisfaction is assessed by a 5point scale: 4: Extremely satisfied3: Very satisfied 2: satisfied 1:Slightly satisfied 0: Not satisfied.