Evaluating the Effects of an Online Positive Mental Health BMI Learning Program on Psychological Health in Patients With Myasthenia Gravis and Its Association With Adverse Childhood Experiences
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 77
- 试验地点
- 1
- 主要终点
- Change in the indicator of mental health BMI on well-being (mBMI) Score from baseline to post-intervention
研究概览
简要总结
This study evaluated psychological health in patients with myasthenia gravis (MG) using an online behavioral program called the "Positive Mental Health BMI Learning Program." The program consisted of four short video units focused on interpersonal support, emotional regulation, and personal meaning. Patients receiving care in the neurology outpatient clinic were invited to complete questionnaires before and after viewing the online program. Psychological well-being, depressive symptoms, daily functioning, and quality of life were assessed to describe participants' mental health status and changes observed over the course of the program.
详细描述
Participants completed sociodemographic questionnaires, adverse childhood experiences (ACEs) assessments, and four psychological and disease-related measures: the Myasthenia Gravis Activities of Daily Living Scale (MG-ADL), the Myasthenia Gravis Quality of Life 15-item scale (MG-QOL15), the mental health BMI indicator (mBMI), and the Patient Health Questionnaire-9 (PHQ-9). The study collected baseline data prior to the online program and post-intervention data after completion of the four video units. Analyses examined associations between ACE exposure and psychological measures, as well as changes in clinical and psychological indicators across the intervention period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
盲法说明
This was an open-label study in which no masking was used. All participants and investigators were aware of the behavioral intervention being provided.
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a confirmed diagnosis of myasthenia gravis (MG) based on acetylcholine receptor antibody testing, single-fiber electromyography, repetitive nerve stimulation, or chest computed tomography.
- •Individuals able to clearly express their own intentions.
- •Individuals without cognitive impairment or psychiatric disorders.
- •Individuals who are able to use Facebook and who agree to participate in the study and provide written informed consent.
排除标准
- •Individuals who do not have a diagnosis of MG.
- •Patients who are unable to communicate adequately in Mandarin, Taiwanese, English, or written form.
- •Individuals with head trauma, psychiatric symptoms, or cognitive impairment that may interfere with verbal expression.
结局指标
主要结局
Change in the indicator of mental health BMI on well-being (mBMI) Score from baseline to post-intervention
时间窗: Baseline to 4 months
The indicator of mental health BMI (mBMI) is a measure of positive psychological well-being that includes three domains: 1. Befriend (B), representing interpersonal support and closeness 2. Mindfulness (M), representing emotional stability and awareness 3. Identity (I), representing self-worth and meaning. Scores were collected before the intervention and after completion of the four-unit online program to evaluate changes in psychological well-being.
次要结局
- Change in Patient Health Questionnaire-9 (PHQ-9) Score from baseline to post-intervention(Baseline to 4 months)
- Change in Myasthenia Gravis Quality of Life 15-item (MG-QOL15) Score from baseline to post-intervention(Baseline to 4 months)
- Change in Myasthenia Gravis Activities of Daily Living (MG-ADL) Score from baseline to post-intervention(Baseline to 4 months)
研究者
Jiann-Horng Yeh
Vice Superintendent, Professor of Neurology, Shin Kong Wu Ho-Su Memorial Hospital
Shin Kong Wu Ho-Su Memorial Hospital