A Comparative Study of Vitamin D Serum Levels in Monosymptomatic Enuretic Children and Non-enuretic Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Vitamin D level
研究概览
简要总结
We are group of researchers interested in causes and management of nocturnal enuresis, we embarked on this research on 2020 and we reached promising results regarding the role of vitamin D serum level in etiology and management of monosymptomatic enuresis.
详细描述
this research was conducted as a comparative study regarding serum vitamin D levels in monosymptomatic enuretic and non enuretic children, also we compared urine osmolality and nocturnal polyuria in both groups and we found that low vitamin D levels are correlated with low nocturnal urine osmolality and increased incidence of nocturnal polyuria
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 5 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with PMNE.
- •which was defined as bedwetting frequency of 3 or more nights per week for at least 2 weeks of observation.
- •Didn't receive any previous treatment for enuresis.
排除标准
- •Patients with non-monosymptomatic enuresis (associated with storage and/or voiding symptoms). -Patients with anatomical abnormalities (Meatal stenosis, Hypospadias, Epispadias, etc.).
- •Patients with neurological diseases.
- •Patients with Renal impairment.
- •Patient with previous pelvic, urological or brain and spinal cord surgery.
- •Patients with chronic constipation and irritable bowel habits.
- •Patients with active urinary tract infection.
- •Patients who are on vitamin D supplements.
结局指标
主要结局
Vitamin D level
时间窗: through study completion, average 1 year.
low vitamin d levels in enuretic group
次要结局
- nocturnal polyuria(through study completion, average 1 year.)
- low nocturnal urine osmolality(through study completion, average 1 year.)
研究者
Diaa Mostafa
Associate Professor
Ain Shams University