Enhancing psychotherapy for bulimia nervosa and binge eating disorder

Phase 1

Completed

• Conditions: Bulimia nervosa and binge eating disorder; Binge eating disorder; Diet and Nutrition - Other diet and nutrition disorders; Mental Health - Eating disorders

• Registration Number: ACTRN12605000721606
• Lead Sponsor: Health Research Council of New Zealand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-11-09
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

i) current primary diagnosis of BN or BED; ii) Body mass index (BMI) > 17.5.

Exclusion Criteria

Current severe major depression (HDRS>20); ii) current severe psychoactive substance dependence; iii) current or past bipolar I disorder or schizophrenia; iv) developmental learning disorder or cognitive impairment; v) major medical or neurological illness; vi) current severe medical complications of an eating disorder; vii) currently taking psychoactive medication and unwilling to undergo a supervised drug wash-out period (the longer of two weeks or five drug half-lives); viii) failure to respond to a previous adequate trial of one of the psychotherapies in this study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To examine whether it is possible to improve the outcome of BN and BED treatment by enhancing cognitive component of standard CBT. Standard CBT will be compared with two enhanced forms of CBT - schema therapy and nutrition and appetite enhanced CBT.[End of treatment (12 months)];To examine whether it is possible to improve the outcome of BN and BED treatment by enhancing the nutritional component of standard CBT. Standard CBT will be compared with two enhanced forms of CBT - schema therapy and nutrition and appetite enhanced CBT.[End of treatment (12 months)];Binge eating (frequency of binges per week)[End of treatment (12 months)]

Secondary Outcome Measures

Name	Time	Method
i) Recovery, defined as abstinence from binging, purging and the absence of any eating disorder diagnosis[Outcomes are measured at end of treatment (12 months). ];ii) Clinician-rated EDE subscales (sum): Restraint, bulimia, eating concerns, weight concerns, shape concerns[Outcomes are measured at end of treatment (12 months). ];iii) Clinician-rated: Global Assessment of Functioning, Axis V of DSM-IV[Outcomes are measured at end of treatment (12 months). ];iv) Weight[Outcomes are measured at end of treatment (12 months). ];v) Number of days per week on which binge eating occurs[Outcomes are measured at end of treatment (12 months). ];vi) Cliinician-rated: Global Eating Disorder Status[Outcomes are measured at end of treatment (12 months). ];vii) Eating disorder symptoms: number of purges, dietary restriction[Outcomes are measured at end of treatment (12 months). ];viii) Self-report: EDI subscales: Drive for Thiness, Body Dissatisfaction, Bulimia.[Outcomes are measured at end of treatment (12 months). ]