Pre-operative Prehabilitation in Cancer Surgery - Objective Recovery Assessment

简要总结

主要结局

次要结局

• Appetite and eating behavior is evaluated with Disease Related Appetite Questionnaire (DRAQ)(12 weeks)
• Time from surgery until the day of first dose of adjuvant chemotherapy (among liver and rectal cancer patients for whom postoperative chemotherapy is planned)(90 day after surgery)
• 30 s chair stand test(12 weeks)
• Test of hand grip strength(12 weeks)
• Cardiopulmonary exercise test with ventilatory gas analysis(12 weeks)
• Appetite and eating behavior is evaluated with Eating Symptom Questionnaire (ESQ)(12 weeks)
• Weekly alcohol consumption(12 weeks)
• Sum of all complications in each patient (comprehensive complication index, CCI)(90d after surgery)
• Clinical Frailty Scale(12 weeks)
• International Physical Activity Questionnaire(12 weeks)
• Length of hospitalization(90d after surgery)
• Grade of sarcopenia(12 weeks)
• Incremental cost-effectiveness ratio(2 years after surgery)
• The presence of malnutrition evaluated with the Global Leadership Initiative on Malnutrition (GLM) criteria(12 weeks)
• Overall survival(5 years)
• 4-week point prevalence of smoking abstinence (among baseline smokers)(12 weeks)
• Episodes of heavy drinking per month(12 weeks)
• The most severe complication occurring(90d after surgery)
• Time to functional recovery of physical status as compared to baseline values(90d after surgery)
• The frequency of failures to go through the full treatment program as planned at the first MDT (including, but not limited to, the full oncological chemotherapy program, radiation treatment and final surgery)(90 days)
• Quality of Life (QoL)(2 years after surgery)
• Proportion of patients not able to receive all treatment despite no dissemination of disease(90 day after surgery)