The effect of nutrition in cardiac surgical patients on heart function.
Completed
- Conditions
- Coronary artery disease, heart failure.Coronair lijden, hartfalen.
- Registration Number
- NL-OMON20597
- Lead Sponsor
- Academic Medical Center University of Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 48
Inclusion Criteria
1. Patients who have to undergo an off-pump coronary artery bypass grafting (CABG) operation;
2. Aged 18 till 81 years.
Exclusion Criteria
1. Combined valve and CABG procedures;
2. Aged <18 and > 80 years;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study outcomes are concentrations of amino acids, and methylated arginines in blood plasma and cardiac tissue, and cardiomyocytes functioning assessed by histology.
- Secondary Outcome Measures
Name Time Method The secondary study outcomes are cardiac perfusion, and cardiac fatty acid and glucose metabolism, measured by myocardial scintigraphy and positron emission tomography.