Randomised controlled trial comparing point-of-care testing for respiratory viruses with standard clinical care in adults hospitalised with acute respiratory illness
- Conditions
- Acute respiratory illnessRespiratory
- Registration Number
- ISRCTN90211642
- Lead Sponsor
- niversity Hospital Southampton Foundation NHS Trust
- Brief Summary
2017 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/28166743 2017 results in: https://www.ncbi.nlm.nih.gov/pubmed/28392237 2018 post-hoc analysis in: https://www.ncbi.nlm.nih.gov/pubmed/29946003
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 720
1. Aged 18 years old or over
2. Capacity to provide written informed consent and is able and willing to adhere to the study procedures
3. Is a patient at Southampton General Hospital Acute Medical Unit (AMU) or Emergency Department (ED)
4. Can be recruited to the study within 24 hours of first triage by ED staff or within 24 hours of arrival on AMU (if admitted directly to AMU)
5. Has an acute respiratory illness and/or fever >37.5°C
6. Duration of illness less than or equal to 7 days
An episode of acute respiratory illness is defined as an acute pulmonary illness (including pneumonia, bronchitis and influenza-like illness) or an acute exacerbation of a chronic respiratory illness (including exacerbation of chronic obstructive pulmonary disease, asthma or bronchiectasis).
1. A palliative approach is being taken by the treating clinicians
2. Previously included in this study (first season only)
3. Declines nasal or pharyngeal swabbing
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients treated with antibiotics: measured retrospectively from case notes for the entire duration of hospitalisation or at 30 days, whichever is shortest
- Secondary Outcome Measures
Name Time Method