Pre- and neonatal screening of hemoglobinopathies: a prospective study.
Completed
- Conditions
- Hemoglobinopathies
- Registration Number
- NL-OMON26283
- Lead Sponsor
- o
- Brief Summary
P.C. Giordano et al. A confidential inquiry estimating the number of patients affected with sickle cell disease and thalassemia major confirms the need for a preventive strategy in the Netherlands. hemoglobin (2004),28: 287-296 <br><br> Disorders of hemoglobin. Genetics, pathophysiology and clinical managment. Edit by Steinberg et al. Cambridge Univ. Press 2001
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 2000
Inclusion Criteria
1. Pregnant females before the 16th week of pregancy and newborns.
2. Informed consent.
Exclusion Criteria
Known hemoglobinopathy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Carrier frequence of hemoglobinopathies.
- Secondary Outcome Measures
Name Time Method 1. Serum ferritin;<br /><br>2. Compliance to prenatal testing;<br /><br>3. Cost-Effectiveness.