Oral iron supplemntation for anemia in ulcerative colitis

Not Applicable

• Conditions: Health Condition 1: K51- Ulcerative colitis

• Registration Number: CTRI/2023/02/049438
• Lead Sponsor: Postgraduate Institute of Medical Education and Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2023

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Ulcerative colitis in remission as defined by Mayo score

- Iron deficiency Anemia with Hemoglobin between 8 gram/dL to 12 gram/d

Exclusion Criteria

- Severe anemia (Hemoglobin less than 8 gram/dL)

- Patients with active disease of ulcerative colitis

- Patients with history of blood transfusion and iron therapy within last 12 weeks

-Patients who deny consent or do not agree for follow up

-Pregnant or lactating women

-Age < 18 years or > 100 years

-Crohnâ??s disease

-Additional causes of anemia like celiac disease, thalassemia and other hemoglobinopathies.

-Comorbidities like coronary artery disease, CKD or CLD requiring immediate correction of anemia

- Previous intolerance to oral iron therapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean Increase in the Hemoglobin levelsTimepoint: 8 weeks

Secondary Outcome Measures

Name	Time	Method
Change in serum ferritinTimepoint: 8 weeks;Change in transferrin saturation levelsTimepoint: 8 weeks;Drug adherenceTimepoint: 8 weeks;Frequency of gastrointestinal side effectsTimepoint: 8 weeks