Sensitivity of preoperative COVID-19 swabs in young childre

• Conditions: J35.2; J35.1; U07.1; Hypertrophy of adenoids; Hypertrophy of tonsils; COVID-19, virus identified

• Registration Number: DRKS00029030
• Lead Sponsor: St. Elisabeth Krankenhaus

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-06-30
• Study Start: 2022-09-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

Children = 6 years
- Planned adenotomy and/or tonsillotomy under general anesthesia
- Consent from a parent to participate in the study

Exclusion Criteria

- Positive preoperative SARS-CoV-2 PCR swab
- Participation in another clinical study within the last month prior to study entry

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
egative predictive value of a SARS-CoV-2 PCR test in small children: SARS-CoV-2 rapid antigen test naso- and oropharynx (preoperative and intraoperative), PCR smear in the nasopharynx and oropharynx (preoperative), PCR smear in the oropharynx and nasopharynx and on removed tissue (separately, intraoperative), SARS-CoV-2 antibodies in serum (intraoperative, 5 ml serum)

Secondary Outcome Measures

Name	Time	Method
- Prevalence of COVID-19 in young children.<br>- Differences between oropharyngeal and nasopharyngeal swabs in this patient group.<br>- Value of parental self-tests and rapid intraoperative tests.