TCTR20200201001已完成4 期
Comparative efficacy between paracetamol and paracetamol/tramadol in postoperative intertrochanteric fracture: A Noninferiority randomized control trial double-blind study
department of orthopedic hadyai hospital0 个研究点目标入组 60 人开始时间: 2020年2月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
The overall mean VAS from postsurgery to discharge day were slightly higher in paracetamol alone group compared to paracetamol/tramadol group. However, according to the 2.0 point of noninferiority margin of pain, the outcome parameters were not clinically different between two groups. In the case of a patient's acceptance of the side effects of opioids, prescribing tramadol may be acceptable to decrease the mean pain scores even the pain amelioration was slightly lower compared to paracetamol alone.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 60 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •The intertrochanteric fracture patients who were diagnosed by hip X-ray plain film assessing with anteroposterior (AP) view and lateral cross table, classified by AO/OTA classification (Figure 1), were eligible to enroll on the study. All patients were aged > 60 years, diagnosed with intertrochanteric fracture as aforementioned at either emergency room (ER) or out-patient department (OPD) service. Furthermore, all patients were required to understand the Thai language in terms of written and spoken abilities.
排除标准
- •patients with multiple traumas, liver cirrhosis, disorientation, and a history of drug allergy to paracetamol, morphine, and tramadol were excluded from the study. According to the surgical procedures, the patients who were undergoing procedures other than cephalomedullary nail were also considered excluded from the study.
研究者
相似试验
进行中（未招募）
1 期
Efficacy and safety of paracetamol in the treatment of patent ductus arteriosus in preterm infants.Patent ductus arteriosusMedDRA version: 16.1Level: LLTClassification code 10034190Term: PDA Repair patent ductus arteriosusSystem Organ Class: 100000004865EUCTR2013-003883-30-ITAziende Chimiche Riunite Angelini Francesco ACRAF S.p.A109
进行中（未招募）
1 期
Effect of paracetamol versus paracetamol combined with pregabalin versus paracetamol combined with pregabalin and dexamethason on pain and opioid requirements in patients scheduled for abdominal hystrectomy.EUCTR2004-005271-42-DKDept. of Anaestesiology, University hospital in Glostrup
进行中（未招募）
不适用
Effect of paracetamol versus paracetamol combined with pregabalin versus paracetamol combined with pregabalin and dexamethason on pain and opiod requirements in patient sheduled for tonsilectomiePatients scheduled for toncilectomia need postoperative paintreatment. Morphine has sideeffects: Nausea, vomiting, sedation and dizziness. These sideeffects are og couse unpleasent for the patient and sometimes prolongs there stay in the hospital.EUCTR2005-003115-74-DKDept. of Anaestesiology, University hospital in Glostrup
进行中（未招募）
1 期
Effect of paracetamol versus paracetamol combined with pregabalin versus paracetamol combined with pregabalin and dexamethason on pain and opioid requirements in patients scheduled for a primary total hipreplacementEUCTR2005-002483-28-DKDept. of Anaestesiology, University hospital in Glostrup120
已完成
4 期
Comparison of Two Different Doses of Paracetamol for Post-Operative Pain ReliefAdult Patients Scheduled for 3rd Molar Teeth ExtractionsNCT00286650University of Otago18