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Randomized controlled trial to determine the efficacy and safety of ramosetron hydrochloride in male patients with diarrheal-predominant IBS symptom

Not Applicable
Conditions
Irritable bowel syndrome
Registration Number
JPRN-UMIN000005237
Lead Sponsor
Department of Hepatology and Pancreatology, Kyushu University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Male
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients who have bowel move disturbance by organic lesion such as IBD(UC and crohn disease etc.) and cancer. 2) Patients suspected of obstruction in stomach and intestines, and with a history of total gastric resection or bowel resection but not appendicectomy 3) Patients with serious complications (liver, kidney, heart, lung, circulatory, or metabolic disorder) 4) Patients with a history of drug allergy 5) Patients who are taking psychotropic drug 6) Others, including patients who are unfit for the study as determined by the attending doctor

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
IBS-QOL-J
Secondary Outcome Measures
NameTimeMethod
1.Subjective symptom (abdominal pain, abdominal fullness) 2.Defecation (bowel frequency, stool form) 3. Blood cytokine level 4.Serum concentration of serotonin 5.Patient's impression
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