Registre Tumeurs Endocrine - Eurocrine
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- Postoperative complications (endocrine surgical procedure)
研究概览
简要总结
This registry aims to collect informations about patients with endocrine tumors (Thyroid, Parathyroid, Adrenal, Endocrine Pancreas, Endocrine Digestive Tube) who undergo endocrine surgical procedures. This registry is part of the Eurocrine Project.
详细描述
The EUROCRINE project aims to decrease morbidity and mortality of rare endocrine tumours, by means of a pan-European database. Recording and accessing data at the European level, makes it possible to identify these tumours, which cannot be distinguished at local or national level, because of their extreme rarity. Dissemination of results aims to raise clinical standards and reduce differences in practise between clinics and member states, and thereby diminish morbidity and mortality. Comparison of practice and outcomes will be especially interesting for centres wanting to improve their standards to what is currently considered best practice. EUROCRINE will be a key means by which the medical profession, researchers, health policy makers, and not least patients, can benefit from an increase in knowledge related to diagnosis, treatment, and future clinical research in the field of rare endocrine tumours.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who undergo surgical procedures for endocrine tumors at the University Nancy Brabois Hospital
排除标准
- •unable to receive clear information
- •refusal to sign the consent form
结局指标
主要结局
Postoperative complications (endocrine surgical procedure)
时间窗: 12 months after surgical procedure
morbidity rate in percentage (%)
次要结局
- PET scanning(Baseline)
- Postoperative complications severity (endocrine surgical procedure)(12 months after surgical procedure)
- CT imaging before endocrine surgical procedure (Tumor characteristics)(Baseline)
- Aldosterone plasma levels(Baseline and up to 12 months after surgical procedure)
- Intraoperative systolic arterial pressure(Intraoperative)
- Plasma free metanephrines(Baseline and up to 12 months after surgical procedure)
- Postoperative mortality (endocrine surgical procedure)(12 months after surgical procedure)
- Bone mineral density(Baseline)
- Intraoperative diastolic arterial pressure(Intraoperative)
- Plasma renin activity(Baseline and up to 12 months after surgical procedure)
- CT imaging before endocrine surgical procedure (Coronary artery score)(Baseline)
- CT imaging before endocrine surgical procedure (Sarcopenia)(preoperative period)
- Parathormone plasma levels(Baseline and up to 12 months after surgical procedure)
研究者
Laurent BRUNAUD
investigator
Central Hospital, Nancy, France