Preoperative Prognostic Factors and Predictive Score in Patients Operated on for Combined Cataract and Idiopathic Epiretinal Membrane.

Centre Hospitalier Universitaire Dijon0 sites142 target enrollmentApril 2009

ConditionsEpiretinal Membranes

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Epiretinal Membranes
Sponsor: Centre Hospitalier Universitaire Dijon
Enrollment: 142
Primary Endpoint: Best corrected visual acuity
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Retrospective interventional case series study reporting preoperative clinical and anatomical factors associated with visual recovery 1 year after combined cataract and idiopathic epiretinal membrane surgery. Age, duration of symptoms, and preoperative best corrected visual acuity appeared to be reliable prognostic factors. Combining these factors with analysis of the photoreceptors' inner and outer segments junction in spectral-domain optical coherence tomography provides a predictive score to estimate individual chances of good visual recovery

Registry

clinicaltrials.gov

Start Date

April 2009

End Date

October 2013

Last Updated

11 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Centre Hospitalier Universitaire Dijon

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•symptomatic idiopathic epiretinal membrane operated on between April 2009 and September 2012 at the university hospital of Dijon, France.
•All patients signed informed consent for the surgical procedure.

Exclusion Criteria

•Patients were excluded if they presented any cause of secondary epiretinal membrane (including diabetic retinopathy, vein occlusion, ocular inflammation, retinal detachment, or previously vitrectomized eye), high myopia (axial length ≥ 26 mm or spherical equivalent ≥ 6 diopters), severe media opacities with weak SD-OCT signal strengths, or any macular or optic nerve disease. Patients with a follow-up of less than 12 months were excluded and only one eye was included in those with bilateral epiretinal membranes.

Outcomes

Primary Outcomes

Best corrected visual acuity

Time Frame: 1 year after the surgery

Best corrected visual acuity 1 year after the surgery, and preoperative factors associated with this visual outcome (age, duration of symptoms, initial best corrected visual acuity, and optical coherence tomography findings)