A Compartmental Analysis of HIV Reservoirs and Immune Reconstitution (C)

University of Minnesota1 site in 1 country21 target enrollmentSeptember 2008

ConditionsHuman Immunodeficiency Virus

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Human Immunodeficiency Virus
Sponsor: University of Minnesota
Enrollment: 21
Locations: 1
Primary Endpoint: Herpes Simplex Virus - Type 2 shed rate
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this study is to find out if the process of HIV replication in the lymph tissue and gut tissue of people taking HIV drugs causes long-term damage to the ability of the gut to protect you from other infections and health problems.

Registry

clinicaltrials.gov

Start Date

September 2008

End Date

January 2013

Last Updated

11 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Minnesota

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•HIV+ individuals
•Seropositive for HIV
•On ART for at least 12 months
•Seropositive for Herpes Simplex Type 2 and Cytomegalovirus
•Age ≥ 18 years
•Negative pregnancy test for eligible women of childbearing potential
•HIV- individuals
•Seronegative for HIV
•Seropositive for Herpes Simplex Type 2 and Cytomegalovirus
•Age ≥ 18 years

Exclusion Criteria

•Taking daily suppressive therapy for Herpes Simplex Type 2
•Contraindication to surgical \& endoscopic procedures (as judged by PI)
•Psychiatric or psychological illness that would make adherence to protocol procedures unlikely
•Pregnancy