CTRI/2019/01/017285尚未招募Phase 3 4
Efficacy,Tolerability And Side effects of 35% Trichloroacetic acid and 50% Glycolic acid peel in Acanthosis nigricans-Single Blinded Randamonized Control Trial
Jhanaranjane m1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2019年1月30日最近更新:
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To asses the clinical outcome of 35% Trichloroacetic acid and 50% Glycolic acid peel in Acanthosis nigricans.
研究概览
简要总结
1.Acanthosis nigricans is characterized by thickened skin with a velvety texture distributed over neck,axilla,antecubital and popliteal fossae, groin folds, histopathologically characterized by papillomatosis and hyperkeratosis of skin.
2.TCA and glycolic acid peel has the property of exfoliation causing destruction of epidermis with subsequent repair and rejuvenation.
3.They also have anti-inflammatory,keratolytic and antioxidant effects that enhance rejuvenation of the skin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients with Acanthosis nigricans between 18 to 25years giving consent for procedure.
- •2.Both gender are included.
排除标准
- •1.pregnant female 2.patients with recurrent herpes infection,hypertrophic scars,keloid,active dermatitis 3.patients not willing for study.
- •4.patient less than 18years and more than 55years.
结局指标
主要结局
To asses the clinical outcome of 35% Trichloroacetic acid and 50% Glycolic acid peel in Acanthosis nigricans.
时间窗: Clinical outcome assesed after 5 sittings of application
次要结局
- To asses the tolerability and side effects of 35% Trichloroacetic acid and 50% Glycolic acid peel in Acanthosis nigricans(Tolerability and side effects assesed every session of topical application.)
研究者
研究点 (1)
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