The Use of Narrow Band Imaging in Screening Colonoscopy
Not Applicable
Completed
- Conditions
- Colonoscopy
- Interventions
- Procedure: Narrow Band Imaging
- Registration Number
- NCT00908648
- Lead Sponsor
- Valduce Hospital
- Brief Summary
Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa. Conflicting data exist on the ability of NBI in to improve detection of colonic neoplasm; the impact of NBI is being tested in several screening scenarios. The investigators evaluated whether the routine use of NBI, compared to white light (WL), during the withdrawal phase of screening colonoscopy improved adenoma detection.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 206
Inclusion Criteria
- 50-69 year-old asymptomatic subjects at average-risk of CRC
- positive FOBT participating in a national mass-screening program and referred for colonoscopy
Exclusion Criteria
- ongoing anticoagulation therapy
- inadequate bowel cleansing
- incomplete colonoscopy
- refusing to participate
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 2 Narrow Band Imaging Narrow Band Imaging
- Primary Outcome Measures
Name Time Method Adenoma Detection duration of colonoscopy procedure Detection of adenoma, defined as the number of patients with \> 1 adenoma, under White Light or NBI visualization
- Secondary Outcome Measures
Name Time Method Detection of Flat and/or Depressed Adenomas duration of colonoscopy procedure number of patients with at least 1 flat and/or depressed adenoma