Impact of Biliopancreatic Limb Length of 60cm vs 100cm in Roux-en-Y Gastric Bypass on Bone Mineral Density 2 Years After Surgery
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Osteopenia
- Sponsor
- Hospital General Universitario Elche
- Enrollment
- 200
- Primary Endpoint
- Bone mineral density
- Last Updated
- 5 years ago
Overview
Brief Summary
Patients will be randomized into 2 groups:
- Group 60: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic limb length of 60cm
- Group 100: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic limb length of 100cm
Bone mineral density will be evaluated before surgery and 2 years after it.
Detailed Description
Patients will be randomized into 2 groups: * Group 60: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic limb length of 60cm * Group 100: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic limb length of 100cm Alimentary limb will be constant in both groups (150cm length) Bone mineral density will be evaluated before surgery and 2 years after it, by means of X ray absorptiometry (DEXA). Changes in bone mineral density in lumbar column will be assessed.
Investigators
Jaime Ruiz-Tovar, MD, PhD
Department of Surgery
Hospital General Universitario Elche
Eligibility Criteria
Inclusion Criteria
- •Body mass index \>40 Kg/m2
- •Body mass index \>35 Kg/m2 associated to obesity related comorbidities
Exclusion Criteria
- •Bone pathologies
- •Active neoplasms
- •Disorders in calcium or vitamin D metabolism
Outcomes
Primary Outcomes
Bone mineral density
Time Frame: 2 years after surgery
Bone mineral density will be evealuated by absorptiometry at the level of lumbar column