Utah Study Evaluating Apneic Oxygenation for Emergency Department Intubation

Not Applicable

• Conditions: Intubation

• Registration Number: NCT02961933
• Lead Sponsor: Intermountain Health Care, Inc.

Brief Summary

This study will determine rates of first pass success without hypoxemia in emergency department intubations with and without the use of apneic oxygenation by nasal cannula.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-11-01
• Study First Submitted QC: 2016-11-08
• Study First Posted: 2016-11-11
• Study Start: 2016-12
• Primary Completion: 2020-01
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-10
• Last Update Posted: 2020-02-11
• Study Completion: 2020-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Patients requiring emergent Rapid Sequence or Delayed Sequence endotracheal intubation with administration of a neuromuscular blocker (Succinylcholine, Rocuronium)

Exclusion Criteria

• Known prisoners
• Patients in cardiac arrest
• Patients who are intubated without the use of neuromuscular blockade (i.e., cardiac arrest, awake intubation).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
First pass success without hypoxemia	10 minutes

Secondary Outcome Measures

Name	Time	Method
Change in peri-intubation saturation	0, 30, 60 and 120 seconds
Saturation at time of tube placement	10 minutes
Time to desaturation <93%	measured time until saturations drop below 93% during the peri-intubation period, up to 10 minutes
Saturation at post intubation	0, 30, 60, and 120 seconds

Trial Locations

Locations (1)

Intermountain Medical Center; 🇺🇸 Murray, Utah, United States