A Controlled Comparative Clinical Trial To Evaluate The Effect Of Dantyadi Kashaya Yoni Prakshalana In Shweta Pradara w.s.r. to Candida Vaginitis

·      Abnormal vaginaldischarge is a frequent complaint of women seen in the gynecologic clinic. Thedischarge may range from excess of normal to one which is a part of widespectrum of diseases. Candidavaginitis is caused by Candida albicans a gram - positive yeast like fungus. The patientcomplains of vaginal discharge with intense vulvovaginal pruritis. In Ayurveda, the word Shwetapradara has not appeared in the BruhatTrayis. Commentator *Chakrapani,*and Samhitas like Sharangadhra Samhita have used the word Shweta Pradara for white vaginalDischarges. Though Kaphadosha involvementis directly not mentioned but the characteristic clinical feature like Sneha, Sheeta, Shukla, Drava etc are that of Kapha thus Shweta Pradara is a Kaphaja Vyadhi.Since the pruritis is out of proportion to discharge this can be correlated toCandida vaginitis.

·      Panchavalkala Kashaya has been taken as standard drug and the combinationof Guduchi, Triphala and Danti (Dantyadi) Kashaya is takenas trial drug as Dantyadi Kashaya contains the drugs that are mainly Tridoshahara,Krumighna, Vishaghna & Vedanasthapana. Here is an attempt to see andcompare the effect of these formulations in management of Shweta Pradara(Candida vaginitis).

·      This is a randomized comparativeclinical study. Total 40 patients of Shweta pradara who fulfills theInclusion Criteria and having Classical sign and symptoms of Shweta pradara willbe selected from the OPD and Medical camps conducted by SDM Trust’s PadmaAyurvedic Hospital and Research Centre, Terdal. These patients are randomlydivided into two groups A and B. Group A will be given Dantyadi Kashaya yoniprakshalanaand Group B given Panchavalkala Kashayayoniprakshalana. Consent will be taken from patient andCase details will be recorded in separate case report form (CRF).  Total Study duration will be 30 days and contain9 visits (0th– 7thday, 15th day, 30thday), which includes administration of trial drug for 7days and post medicationfollow up on 15th& 30th day. After study, data willbe collected from case report form (CRF) and statistically analysed by usingappropriate parametric and nonparametrictests and results will be obtained. Onthat basis of results, conclusion will be drawn.

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