Estimation of efficacy of Reduced form of Coenzyme Q10 (Ubiquinol) gummi on oral function in healthy people
- Conditions
- one
- Registration Number
- JPRN-UMIN000024406
- Lead Sponsor
- Tsurumi University School of Dental Medicine
- Brief Summary
At the end of study, along with a significant increase of the CoQ10 level in saliva (p = 0.025*, d = 0.65), there was a significant increase of the saliva flow rate (p = 0.048*, d = 0.66) in the ubiquinol candy group compared to the placebo group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Not provided
1.under medication 2.take medicine and food that might impact the outcome measure 3.Patient of serious disease such as liver disease,renal disease,heart disease,cancer 4.Pregnant and women who wish to pregnant in this study period 5.Sjogren's syndrome patients 6.The person that the eating habits are extremely irregular, Person of shift work, Person of graveyard shift 7.The person indicating the allergic reaction to experimental diet 8.The person entry another clinical study which ongoing or within four weeks after other clinical study end or with the plan to participate in other clinical study 9.Doctor did not allow to entry to this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method CoQ10 concentration in saliva Amount of saliva secretion Anti-oxidative activity of saliva Oxidative stress in saliva RSST biting force These items will be determined at 0,8weeks after intake.
- Secondary Outcome Measures
Name Time Method