Evaluation of Diprospan Injection to the Knee on Rehabilitation of Patients After TKR of the Contralateral Knee
- Registration Number
- NCT00542139
- Lead Sponsor
- Hadassah Medical Organization
- Brief Summary
This study is performed to assess the influence of intraarticular injection of 2ml Diprospan (wich contains 4mg Betamethasone sodium phosphate and 10mg Betamethasone dipropionate) into osteoarthritic knee in patients who undergo a total knee replacement of their contralateral knee.
The study population will include 50 patients with bilateral knee osteoarthritis, admitted for their first knee replacement surgery. Only patients with older than 50 years with primary osteoarthritis will be included. The patients will be randomized into 2 groups. Intervention group will receive an injection of 2ml Diprospan diluted in 10 ml Bupivocaine. The control group will receive an injection of 10ml of Bupivocaine. All patients will be followed after 6 weeks and three functional rehabilitation and pain scores will be assessed (VAS pain score, Timed Up and Go Score and Functional Ambulatory Category Scale).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
- Age older than 50
- Bilateral primary knee osteoarthritis
- Undergoing knee arthroplasty
- Active infection
- Allergy to medication compounds
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 2 Bupivocaine - 1 Betamethasone -
- Primary Outcome Measures
Name Time Method Visual analogue pain score 6 weeks
- Secondary Outcome Measures
Name Time Method Timed Up and Go Score 6 weeks Functional Ambulatory Category Scale 6 weeks
Trial Locations
- Locations (1)
Hadassah Medical Organization
🇮🇱Jerusalem, Israel