The Effect of Continuous vs Enteral Pump Feeding in Aspiration in Tube Fed Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 222
- 试验地点
- 1
- 主要终点
- pneumonia
研究概览
简要总结
Background:
Tube feeding had been found to be a cause of aspiration pneumonia. Continuous pump feeding at slower rates as compared to bolus feeding may be less associated with aspiration pneumonia.
Methods:
Randomized controlled trial
Subjects:
Patients expected to remain on tube feeding for 4 or more weeks
Outcomes:
- pneumonia, 2) mortality
详细描述
Eligible subjects are randomized into 2 groups by random numbers generated by a computer programme: intermittent bolus feeding versus continuous feeding via a delivery pump.
Baseline Assessment:
Clinical details including background medical diagnoses, indications for enteral feeding, functional status and baseline CXR findings are recorded.
Tube Feeding Regime:
The choice of feeding formula and feeding volume will be guided by 2 dietitians collaborating in this study. Giving sets for continuous pump feeding are changed everyday.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients likely to need tube feeding for another 4 weeks
排除标准
- •Patients already on pump feeding.
- •Active sepsis: fever, abnormal white cell count
- •CXR shadowing
- •Chronic hypoxia (O2 saturation <92% on room air)
- •Patients who have a history of recurrent self-extubation.
- •Short life expectancy (within weeks)
结局指标
主要结局
pneumonia
时间窗: within 4 weeks
次要结局
- mortality(within 4 weeks)