Brain-computer interface and neuromuscular stimulation for rehabilitation following chronic stroke - BCI-NMES-CVA

Defitech Chair in Brain-Machine Interface, EPF0 sites32 target enrollmentMarch 16, 2017

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: I61 - Intracerebral haemorrhageI63 - Cerebral infarctionChronic condition (at least 10 months after occurrence of cerebrovascular accident)
Sponsor: Defitech Chair in Brain-Machine Interface, EPF
Enrollment: 32
Status: Active, not recruiting
Last Updated: 9 years ago

No summary available.

Registry

who.int

Start Date

March 16, 2017

End Date

TBD

Last Updated

9 years ago

Study Type

Interventional clinical trial of medicinal product

Sex

All

Sponsor

Defitech Chair in Brain-Machine Interface, EPF

•1\) Age more than 18 years\-old
•2\) Victim of cerebrovascular accident (stroke)
•3\) Patients in their chronic phase, more than 10 months after stroke.
•4\) Severe paralysis of the arm
•5\) Ability to understand information and ability to give a free and informed consent
•6\) Good eyesight and hearing, or corrected
•7\) First stroke (infarction), preferably ischemic stroke
•8\) Unilateral cortical lesion (left or right hemisphere) or subcortical lesion, lesions of the supra\-pontic corticospinal pathway causing a motor deficit of upper limb
•9\) Paresis / central paralysis of the upper limb (the intervention focuses on upper limb; The presence of other motor deficits is not a criterion of exclusion)
•10\) Ability to understand instructions to perform mental tasks, like mental imagery or attempt of motor activity (more specifically, the ability to imagine/attempt movements of the upper limbs). These capacities are estimated with neurophysiological assessments

•1\) Anything that hampers the proper EEG acquisition (for example, a skin contamination, scalp wound, dermatitis, uncontrolled/coarse muscle activity or an electrically noisy environment)
•2\) Heavy medication affecting the central nervous system (including vigilance)
•3\) Concomitant serious illnesses (comorbidity: fever, infection, metabolic, cardiac arrest)
•4\) Multiple infarctions
•5\) Complete unlilateral spatial neglect
•6\) Inability to perform mental and motor imagery tasks
•7\) Severe inability to understand and communicate (eg, severe aphasia), inability to understand the information given, the objectives of the study or instructions to perform tasks.
•8\) Inability to concentrate for 2 hours.
•9\) Severe dystonia / involuntary movements
•10\) Other concurrent neurological disorders (eg, Parkinson's disease)