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临床试验/CTRI/2026/02/104256
CTRI/2026/02/104256尚未招募不适用

Cue-Based Feeding in Preterm Infants With Short Term Growth And Neurodevelopmental outcome:A Quasiexperimental Study

DR.Meghana K1 个研究点 分布在 1 个国家目标入组 112 人开始时间: 2026年3月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
112
试验地点
1
主要终点
To compare the rate of growth in preterm infants (born less than 37

研究概览

简要总结

Preterm infants need to be able to coordinate sucking, swallowing, and breathing, sustain alert

awake behavior and preserve cardiorespiratory stability to achieve successful oral feeding  . This

develops through a gradual oral motor maturation process that correlates with the emergence

of motor pathways and maturation of the central nervous system, which correlates with the

postmenstrual age (PMA) of the infant . Until these levels of behavioral readiness and oral

motor maturation are reached, preterm infants commonly require gavage feedings which are

given on a schedule to ensure that specific feeding volumes are consumed. Premature infants

often struggle with oral feeding due to underdeveloped skills and immature neurological

systems  . Traditionally, oral feedings in the NICU are based on fixed schedules and volumes,

rather than the infant’s readiness and ability  . This approach can lead to feeding difficulties,

longer hospital stays, and stress for both infants and caregivers.

Cue-based feeding is a more individualized method that focuses on an infant’s behavioral cues

to determine feeding times and amounts . Behavioral cue-based feeding (BCBF) based on close

observation of the infant’s behavioral signals is a method in which caregivers determine how

and when and how much an infant expects to be fed. Each infant is considered an individual

with meaningful behaviors. A gestational age and volume driven approach to feeding therefore

is shifted towards an infant-driven approach  .These cues include signs of hunger, readiness to

suck, and the ability to coordinate sucking, swallowing, and breathing.

Standardized feeding cues

  1. Crying

  2. Quiet alert

  3. Hand-to-mouth activity

  4. Sucking on fingers, fist, or pacifier

  5. Rooting

  6. Inability to settle after position change, diaper change,

or pacifier

Research suggests that cue-based feeding can support safer, more effective feeding

experiences, promote earlier feeding milestones, and possibly reduce the length of hospital

stays.

The benefits of cue-based oral feeding highlights the need for a shift from volume-driven to

infant-driven feeding practices, aligning with developmental care principles  . By recognizing and

responding to each infant’s cues, caregivers can support better feeding outcomes and overall

development  .

研究设计

研究类型
Observational

入排标准

年龄范围
1.00 Day(s) 至 90.00 Month(s)(—)
性别
All

入选标准

  • 1.Who have attained corrected gestation age of 32 weeks or more 2.Have attained complete oral feeding (paladai feeding) for 24hrs
  • Discontinued all parenteral fluids.

排除标准

  • a) Pretern neonate with congenital malformation b)Preterm neonate with chromosomal abnormality c)Preterm nenate with gastrointestinal surgical interventions d)Lack of weight gain for 3 consecutive days after inclusion in study e)Feeding prescribed as per physician discretion e)Preterm neonates treated for Necrotizing enterocolitis, feeding intolerance.

结局指标

主要结局

To compare the rate of growth in preterm infants (born less than 37

时间窗: To compare the rate of growth in preterm infants (born less than 37 | weeks) who received cue based feeding in NICU and after discharge till 40 weeks of | gestation to that of who has received scheduled feeding in the past | and 3 months

weeks) who received cue based feeding in NICU and after discharge till 40 weeks of

时间窗: To compare the rate of growth in preterm infants (born less than 37 | weeks) who received cue based feeding in NICU and after discharge till 40 weeks of | gestation to that of who has received scheduled feeding in the past | and 3 months

gestation to that of who has received scheduled feeding in the past

时间窗: To compare the rate of growth in preterm infants (born less than 37 | weeks) who received cue based feeding in NICU and after discharge till 40 weeks of | gestation to that of who has received scheduled feeding in the past | and 3 months

次要结局

  • 1.To study duration from onset of full oral feeding to discharge(2. To compare the neurodevelopmental outcome using HNNE score at)

研究者

发起方
DR.Meghana K
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Meghana K

KLE Academy of Higher Education and Research

研究点 (1)

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