Does prewarming children improve outcomes in children with cerebral palsy having major lower limb surgery?

Not Applicable

• Conditions: Children with severe cerebral palsy undergoing elective bilateral femoral valgus derotational osteotomies; Anaesthesiology - Other anaesthesiology; Neurological - Other neurological disorders; Surgery - Other surgery

• Registration Number: ACTRN12609000297224
• Lead Sponsor: Royal Children's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-05-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1)Children with severe cerebral palsy undergoing elective bilateral femoral valgus derotational osteotomies
2) Children aged between 5 -20 years
3) Any weight

Exclusion Criteria

1) Any contraindication to inhaled anaesthetic agents (desflurane/nitrous oxide) (eg: malignant hyperthermia)
2) Severe comorbidities that require postoperative admission to intensive care.
3) Contraindications to epidural anaesthesia
(eg: iatrogenic or pathological coagulopathy or platelet dysfunction, local Sepsis, parental refusal to consent)
3) Ambient room temperature > 28 degrees in the pre-surgical centre

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine whether prewarming can prevent hypothermia. Skin temperature and core temperature (tympanic) will be measured pre and post anaesthesia. During anaesthesia, temperature will be measured using an oesophageal temperature probe.[Temperature will measured pre-operatively, intra-operatively and post-operatively every 30 minutes until discharge from the post-anaesthesia care unit (PACU).]

Secondary Outcome Measures

Name	Time	Method
To determine whether prewarming effects the duration of recovery from anaesthesia.[Time spent in the post anaesthesia care unit (from arrival until discharge).];To determine whether prewarming effects the amount of surgical blood loss. To assess intraoperative and postoperative blood loss we will use (a) Weighing packs, (b) Measuring Drains and (c) Haemoglobin Balance method.[Blood loss measured intraoperatively and postoperatively. These measurements will take place at frequent intervals within these periods.];To determine whether effects the rate of wound infections. Wounds will be classified as infected if there was a purulent discharge or painful erythema that lasted for 5 days and was treated with antibiotics within 6 weeks of surgery.[Postoperative wound infection will be assessed during their inpatient stay and also in their scheduled outpatient visits at 3 and 6 weeks post discharge.]