ow-dose oral immunotherapy for food allergies (buckwheat, fruits, walnuts, cashews, hazelnuts, and macadamia nuts).

Not Applicable

Recruiting

• Conditions: food allergy

• Registration Number: JPRN-UMIN000040531
• Lead Sponsor: ational Hospital Organization Sagamihara National Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-26
• Last Update Posted: 17 October 2023
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

1.The subject who has poorly treated atopic dermatitis and bronchial asthma. 2.The subject who seems inappropriate candidate for oral immunotherapy as judged by a medical doctor.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The rate of short-term unresponsiveness* to the middle-dose** after 1 year * Short-term unresponsiveness is defined as "when patients passed the middle-dose oral food challenge after complete avoidance for 2 weeks." ** The middle-dose is defined as "16 g buckwheat noodle, 40 g fruits, and 3 g walnuts, cashews, hazelnuts, and macadamia nuts."

Secondary Outcome Measures

Name	Time	Method
1. Frequency of adverse reactions 2. The rate of short-term unresponsiveness* to the middle-dose** after 2 years, 3 years, 4 years, and 5 years from the start of oral immunotherapy(OIT) 3. Changes of specific IgE, IgG, and IgG4 * Short-term unresponsiveness is defined as "when patients passed the middle-dose oral food challenge after complete avoidance for 2 weeks." ** The middle-dose is defined as "16 g buckwheat noodle, 40 g fruits, and 3 g walnuts, cashews, hazelnuts, and macadamia nuts."