Recherche Et Caractérisation De Nouveaux Gènes Impliqués Dans La Déficience Intellectuelle.

Institut National de la Santé Et de la Recherche Médicale, France1 site in 1 country8,500 target enrollmentDecember 31, 2012

ConditionsIntellectual Disability

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Intellectual Disability
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Enrollment: 8500
Locations: 1
Primary Endpoint: Number of participants with genetic cause identified
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Intellectual disability (ID) occurs in 2 to 3 % of the general population but the cause is identified only in 30 to 60% of cases.

The purpose of this study is to indentify genes involved in ID with new genetics tools (SNP-arrays, next generation sequencing...) and establish genotype-phenotype correlations.

Registry

clinicaltrials.gov

Start Date

December 31, 2012

End Date

December 31, 2022

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•for the patients: Clinical diagnosis of intellectual disbility
•for the unaffected sibs: to be aged at least 3 years
•informed consent

Exclusion Criteria

•absence of informed consent

Outcomes

Primary Outcomes

Number of participants with genetic cause identified

Time Frame: 5 years

Number of participants for which the causative gene of intellectual disability will be identified and number of genes involved in intellectual disability identified with new technologies including microarray and next generation sequencing