Trapeziometacarpal Cartilage imaging in osteoarthritis: feasibility of 7 Tesla Magnetic Resonance Imaging and Optical Coherence Tomography

Withdrawn

• Conditions: degenerative joint disease with loss of cartilage; Osteoarthritis; 10023213

• Registration Number: NL-OMON37270
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

- Age 18 years or older
- Clinical symptoms of trapeziometacarpal osteoarthritis
- Patients is or will be scheduled for trapeziometacarpal joint arthroplasty
- Radiologic evidence for trapeziometacarpal osteoarthritis of at least stage 2 according to the Eaton-Littler classification

Exclusion Criteria

- Not able to understand the written informed consent
- Contra-indications for MRI research
- Contraindications for surgery
- Under 18 years of age
- Radiologic evidence for TMC OA, of less than stage 2 according to the Eaton-Littler classification

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Visualization of TMC cartilage (degeneration) in advanced osteoarthritis using<br /><br>7T MRI and OCT.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are (differences in) measured cartilage thickness,<br /><br>cartilage volume/surface and surface fibrillation between OCT, 7T MRI and<br /><br>histology. </p><br>