To compare two doses of tranexamic acid in reducing bleeding and transfusions in total knee arthroplasty
Phase 1
- Conditions
- Health Condition 1: null- ASA 1. ASA 2
- Registration Number
- CTRI/2018/03/012728
- Lead Sponsor
- Kasturba Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA grade I and II posted for TKA
Age group 40 â?? 70yrs
No known hypersensitivity to Tranexamic acid
No history of coagulation disorders
Exclusion Criteria
Patient refusal
Bleeding disorders
Preoperative haemoglobin less than 9mg/dL
Preoperative blood or blood product transfusion
Known allergy to tranexamic acid
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method reducing bleeding and transfusions in total knee arthroplastyTimepoint: Every 5 minutes for the first half an hour. Half an hourly till 6 hours post first injection.
- Secondary Outcome Measures
Name Time Method decrease in duration of hospital stayTimepoint: discharge on post operative day 2, 3 or 4